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  • Cooling in Large-Area CMOS

    In Scientific Imaging, we are met with unique challenges. Signals from our imaging subject can often be very weak. With the move to CMOS technology, Quantum Efficiency, Read Noise and Dynamic Range are all optimized to work with weak signals.

  • emICCD Cameras Facilitate Use of Trapped Ions for Quantum Research

    Laser-cooled ions in linear Paul traps are quantum systems with remarkable properties. Trapped ions offer an unprecedented degree of preparation and control of their parameters, can be cooled to the ground state, and can be coupled to engineered reservoirs.

  • Improving the Collection Efficiency of Raman Spectroscopy

    Laser Raman spectroscopy is a powerful technology that is successfully used in a variety of scientific research and industrial applications. The cross-section afforded by Raman scattering is typically orders of magnitude lower than that of other optical spectroscopic methods (such as infrared absorption, laser-induced fluorescence, and ultraviolet-visible absorption), which in many cases serves to limit its utility.

  • Improved Spectra with a Schmidt-Czerny-Turner Spectrograph

    For years spectra have been measured using traditional Czerny-Turner (CT) design dispersive spectrographs. Optical aberrations inherent in the CT design can give spectra with poor spectral resolution, low signal-to-noise ratios (SNR) and distorted peak shapes.

  • Automated Wavelength and Intensity Calibration Significantly Improves Spectral Accuracy

    Calibration of dispersive spectral instruments has long been problematic for researchers. When a spectrum is plotted along a pair of axes, the x-axis usually represents wavelength or wavenumbers, while the y-axis represents intensity. Optical spectroscopic equipment manufacturers have all but left the task of determining the accuracy of both scales to the user.

  • LightField Tips & Tricks

    This document focuses on LightField features to enhance the user experience when operating Princeton Instruments spectroscopy systems.When averaging or summing multiple frames, sometimes LightField does not display individual frames as they are collected. Instead, LightField displays the “waiting for first live frame” message.

  • Neuroscience and Electrophysiology

    Electrophysiology is a method that allows us to study the function of electrically active cells, such as neurons. Research on the physiology of neurons and the nervous system is often accomplished at the cellular level using microscopy techniques or further techniques such as patch clamping.

  • Calcium Imaging at Ecole des Mines de Saint-Etienne

    Professor Rod O’Connor and Dr. David Moreau work together to develop flexible, conductive polymer electrode devices to record electrical activity and optical measures of physiology from neurons to study the bioelectrical basis of diseases like epilepsy, Alzheimer’s disease and cancer.

  • Protein Crystallography

    The rapid acceleration of pharmaceutical research has created a need for rapid study of molecular changes in protein crystals after certain drugs are applied. By collecting images of X-ray diffraction patterns from crystallized protein samples, researchers can determine the effectiveness of cancer fighting drugs as well as determine side effects.

  • Wearable glasses enable surgeons to visualize cancerous cells

    Aeon Imaging, LLC has taken a new and more cost-effective approach to confocal imaging that makes use of the rolling shutter method of detection.

  • Global Shutter Imaging

    High-speed, smear-free still image capture is the hallmark of global shutter image sensors. Applications such as traffic management, metrology and robotics inspection all need to image fast-moving objects without smear or distortion.

  • Machine Vision Sensor Review

    Compare performance specifications with 100+ Mono and Color Camera Models.