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  • High Dynamic Range, Hyperspectral and Multidimensional CARS Measurements of Combustion Gases

    Dr. Brian Petersons lab at University of Edinburgh investigates the fluid dynamics and heat transfer in combustion gases with laser based analysis methods and spectroscopy. Combustion chamber like a car engine have steep temperature gradients between the cold walls at 300-400k and burning gas at temperatures of several thousand Kelvin.

  • Ultra-High-Sensitivity emICCD Cameras Enable Diamond Quantum Dynamics Research

    Interest in the various crystal defects found within diamonds is growing quickly amongst physicists and biologists worldwide. This increasing attention is attributable in no small part to the ability of such defects, when embedded in nanocrystals, to function as single-photon sources or as highly photostable, low-cytotoxicity fluorescent biomarkers.1

  • Ultra-Multiplex CARS Spectroscopic Imaging of Living Cells

    Popular molecular imaging techniques are only able to reveal the distribution or behavior of specific molecules within the human body that have been labeled with pigments or fluorescent proteins. Raman spectroscopy, however, allows researchers to identify the components of unlabeled molecules via spectral analysis.

  • Spinning disc confocal microscopy in the NIR-II window

    Near-infrared (NIR) fluorescent is a technique used widely within biological and medical research due to ability for NIR light to penetrate deeply in biological specimens, the high spatiotemporal resolution that it offers, and the capability to image quickly (Fan 2019).

  • Scientific InGaAs Cameras For NIR-II Imaging for Drug Discovery/Small-Animal Research

    For decades, x-ray and UV-vis-NIR detection methods have been used in various scientific, military, and medical applications. Although generally employed to good success, these systems nonetheless have some limitations when utilized for such types of work.

  • Laser Induced Breakdown Spectroscopy for Geological Characterization of Extraterrestrial Minerals

    Prof. Darby Dyar’s research group, at Mt. Holyoke College, is studying the geology of extraterrestrial bodies in the solar system including the Moon, Mars, and Venus. The lab mainly uses different forms of analytic spectroscopy, such as Mossbauer, reflectance, Raman, and x-ray. Her group is also utilizing laser induced breakdown spectroscopy (LIBS) to quantitatively characterize different minerals.

  • Low-Frequency Raman Spectra of Amino Acids Discovery of a Second Fingerprint Region

    A novel astigmatism-free spectrograph design, the Princeton Instruments SCT 320 IsoPlane Schmidt-Czerny-Turner (SCT) spectrograph, is shown to give Raman spectra with better resolution and signal-to-noise ratios than traditional Czerny-Turner (CT) spectrographs.

  • Instrument Automation via National Instruments LabVIEW®

    While many labs use LabVIEW for instrument automation, quite often researchers find it daunting to create their own vi's if a sub-vi for a desired function is not provided by the instrument manufacturer. Teledyne Princeton Instruments provides robust documentation and building blocks to help most users perform their desired automation without any extra effort needed.

  • Using Raman Spectroscopy to Detect Malignant Changes in Tissues

    Accurate, rapid and non-invasive detection and diagnosis of malignant disease in tissues is an important goal of biomedical research. Optical methods, such as diffuse reflectance, fluorescence spectroscopy, and Raman spectroscopy, have all been investigated as ways to attain this goal.

  • Teledyne DALSA’s 16k multifield TDI camera captures multiple images in a single scan

    Teledyne DALSA is pleased to announce that its Linea™ HS 16k Multifield TDI camera is in volume production. The Linea HS 16k Multifield can capture up to three images simultaneously in a single scan using light sources at different wavelengths. Its charge-domain CMOS TDI sensor with 16k x (64+128+64) TDI arrays and a 5x5 μm pixel size, uses advanced wafer-level coated dichroic filters with minimal spectral crosstalk to spectrally isolate the three images. The camera also comes with high-speed CLHS interface, delivering up to 8.4 Gigapixels per second over a single and long length fiber optic cable.

  • Installing PySpin for the Spinnaker SDK on Windows and Linux

    The Spinnaker SDK supports programming in C++, C#, and C languages. For Python users, a PySpin wrapper must also be installed. The following application note describes the steps to install PySpin for use with the Spinnaker SDK.

  • Using the Event Control Feature

    This application note provides information on the Events Control feature in GenICam cameras.