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Total Internal Reflection Fluorescence (TIRF) Microscopy
Fluorescence microscopy is a fundamental set of techniques in the life sciences for visualizing structures in living systems. Typically, a fluorescent molecule, either synthetic or biological, is associated with a structure of interest in a biological sample.
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Super-Resolution Radial Fluctuations (SRRF)
Some super-resolution data cannot be visualized directly, only after images are reconstructed and processed can they be displayed, such as in PALM and STORM. This processing requires specialized algorithms and analysis software, which must be capable of dealing with the large datasets of thousands of frames from 3D, fast-moving dynamic samples with hundreds of data points of varying densities.
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Intravital NIR Imaging
The group of Prof. Gousopoulos at the University Hospital Zurich is focused on researching lymphedema, a condition where lymphatic system dysfunction results in swelling in parts of the body. The group has established a mouse model in order to investigate this disease.
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Microfluidics and Live Cell Imaging
The deMello Group at ETH Zürich is engaged in a broad range of activities in the general area of microfluidics and nanoscale science. Primary specializations include the development of microfluidic devices for high-throughput biological and chemical analysis, ultra-sensitive optical detection techniques
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Single Molecule Micromirror TIRF
The Duderstadt Group are interested in understanding the organization and dynamics of macromolecular complexes, such as the replisome which is responsible for DNA replication.Successful DNA replication is critical for cell survival, and errors within this process have been implicated in many disease pathologies.
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Nanophotonics
Dr. Mivelle’s research lies within the field of nanophotonics and centers around investigations into the interactions between light and matter on the nanoscale to increase understanding of optical properties.
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Kinetix22 Pre-Arrival Guide
Thank you for your interest in the Kinetix22 sCMOS, the next generation in scientific CMOS cameras. This is a guide to help you prepare for the arrival of the Kinetix22, ensuring that the hardware and software of both your PC and microscope/imaging system are capable of making the most of the power of the Kinetix22 and delivering your desired data.
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Single Molecule Spectroscopy at Heidelberg University
Professor Herten leads the Single Molecule Spectroscopy group at Heidelberg University aiming at quantitative analytical approaches in biology and chemistry based on single-molecule data acquired with advanced fluorescence microscopy.The groups research interests range from the development of fluorescent probes for live-cell microscopy to the investigation of chemical reactions on a single-molecule level.
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Single Molecule Tracking PALM
The Carr Lab at the Genome Damage and Stability Centre, University of Sussex, investigates DNA metabolism processes such as DNA replication and repair. They are interested in the challenges cells face during DNA replication and the cellular processes that help the cell overcome replication fork stalling or collapse.
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eSPIM Light Sheet
Prof. Huang’s lab at UCSF aspires to generate a map of the entire proteome of endogenous proteins in human cells. Towards that goal they use and develop novel imaging modalities including eSPIM, a high numerical aperture epi-illumination form of selective plane illumination microscopy (SPIM).
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Imaging Mitotic Dynamics
Research in the Gorbsky lab focuses on the basic mechanisms of how chromosomes assemble and move during cell division in normal cells and in cancer cells, the process termed mitosis. A major emphasis is the mitotic spindle checkpoint pathway that makes sure that each copy of the 23 pairs of chromosomes is distributed equally to each of the daughter cells.
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Single Molecule Tracking
The lab of Prof. Kubitscheck performs a wide range of imaging across different applications including single-molecule tracking and localization, where they examine the export of ribosomal particles through nuclear pore complexes by a number of methods