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  • STORM & Photonics

    The Photonics Group in the Physics Department at Imperial College London develops instrumentation for multidimensional fluorescence imaging – spanning a wide range of applications, from super-resolved microscopy through automated fluorescence lifetime imaging for high content assays to endoscopy and optical tomography.The availability of Scientific CMOS cameras has been transformative for their research because the technology provides unprecedented imaging performance with high resolution and high frame rates. The team particularly uses Scientific CMOS cameras for localization and light sheet microscopy.

  • Live Cardiac 3D Spinning-Disk

    Prof. Francesco Pasqualini is a Harvard-trained bioengineer leading the synthetic physiology laboratory at the University of Pavia, currently researching cardiac development using engineered cell culture platforms.

  • Calcium Imaging at Karolinska Institutet, Sweden

    Dr. Wiktor Phillips is primarily interested in observing the pattern generation of respiratory rhythms in mammals through the study of the pre-Bötzinger complex in the medulla of the brainstem, and whether these patterns are affected by birth and related to respiratory dysfunction in newborns.

  • Super-Resolution Single Molecule Localization

    The Lew lab is creating technology to image multidimensional trajectories of individual molecules in time and space, with one focus on understanding the structural dynamics of amyloid aggregation in diseases like Alzheimer’s.In collaboration with Jan Bieschke, UCL, the lab has developed a single-molecule localization microscopy (SMLM) technique called TAB, transient amyloid binding, to image the structure of amyloid protein aggregates over periods of hours to days.

  • diSPIM Light-Sheet

    Prof. Matthias Weiss and PhD student Ivana Jeremic research challenging problems at the interface of physics and biology, focusing on understanding self-organization processes in living organisms.

  • Dual-Color Voltage Imaging

    Dr. Davide Raccuglia and his team use the model organism Drosophila melanogaster (colloquially known as fruit fly) to study how the brain regulates sleep. Dr. Raccuglia told us more about his research, “What I’m particularly interested in is the functional neural architecture of sensory gates for sleep regulation.

  • Structured Illumination Microscopy (SIM)

    Dr. Guy Hagen, Research Associate from the University of Colorado, Colorado Springs creates high performance image reconstruction methods and open-source software to process super-resolution microscopy data. In 2014 Dr. Hagen released ThunderSTORM, an ImageJ plug-in for automated processing of photo-activated localization microscopy (PALM) and stochastic optical reconstruction microscopy (STORM) data.1

  • Super-Resolution Microscopy at University of California, Berkeley

    The Ke Xu Group at the University of California Berkeley, College of Chemistry is an interdisciplinary lab that combines biophysics, physical chemistry and cell biology. Their goal is to understand how orders emerge in biological systems at the nano-meter scale from the interaction between biomolecules.

  • TIRF Microscopy at the University of Pittsburgh

    Gerry Hammond studies membrane trafficking and intracellular signaling and regulation in the Center for Biologic Imaging at University of Pittsburgh. Working with Simon Watkins, Director of the Center, they use gene editing technology to fuse GFP to endogenous alleles.

  • Single Molecule Imaging at University of Zürich

    The electrostatic properties of macromolecules—specifically, their electrical charge and interior dielectric characteristics— are a vital component of their function as they contribute to the physical basis of mechanisms that range from molecular recognition, signalling and enzymatic catalysis to protein folding and aggregation, and are of fundamental relevance in experiment and theory.

  • High-Speed Starscape Astronomy

    Prof. Richard Gomer at Texas A&M University is involved with astronomy research beyond the reaches of the solar system. Prof. Gomer told us more about his research, “A simple question in astronomy is whether or not there is material associated with the solar system well out past the orbit of Pluto.

  • TIRF Microscopy, Physics of Cellular Interactions Group

    The group of Dr. Ganzinger is interested in the basic physical principles of immunological signaling. The group uses synthetic biology to reconstitute signaling pathways, and single molecule imaging to enable them to understand how receptors and ligands work together to transmit signals through the cell.