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  • Single Molecule Biophysics

    Dr. Christoph Baumann, Lecturer at the University of York, Department of Biology and his group work with advanced imaging techniques to push forward our understanding of spatio-temporal dynamics in the bacterial cell envelope. Using a Photometrics camera, the group was the first to observe that, contrary to expectations, proteins in the outer cell membrane don’t diffuse significantly when tracked, and that new proteins are inserted predominantly at mid-cell during growth.

  • Whole Heart Light Sheet

    Dr. Leonardo Sacconi is a senior researcher at the National Institute of optics and group leader of the Cardiac Imaging Group, which aims to develop novel imaging modalities for research into cardiovascular physiology and pathology. Using techniques such as calcium imaging, multiphoton excitation, and light sheet, Dr. Sacconi is able to investigate both the structure and function of cardiac tissue.

  • Novel Structured Illumination Microscopy

    Prof. Bernd Rieger works with applied physics at TU Delft, and tells us about his research, “We are an applied physics and engineering group researching computational microscopy and building microscope systems, improving spatial resolution and temporal resolution of imaging systems. We start with empty optical tables and then build our systems.”

  • Fluorescence and Electrophysiology

    Prof. Naoki Yamawaki is a neuroscientist at Aarhus University, who told us about his research, “We are interested in understanding how stress affects the neuronal connections and communication in the brain, I am responsible for running the lab, doing experiments, mentoring, teaching students, and more.

  • NIR/VIS Brain Imaging

    The lab of Professor Marc Spehr is working on the olfactory system of mammals and the underlying mechanisms of pheromone detection. Pheromone detection is key for social communication in the animal world

  • Advice On Choosing A Camera For Calcium Imaging

    The key specifications to look for in a camera for calcium imaging will depend broadly on the type of calcium imaging being performed. From the perspective of the camera, the simplest way to divide calcium imaging would be into two application areas; neuronal calcium imaging and cardiac calcium imaging.

  • Digital Interfaces

    Digital interfaces allow scientific cameras (and other imaging or microscopy hardware) to communicate with computers, typically for data transfer so that images acquired during experimentation can be stored for analysis and processing.

  • Intrinsic Signal Optical Imaging

    The brain is one of the most complex objects in the known universe, both in terms of structure and function. This makes imaging the brain an incredibly challenging task, with researchers looking at the movement of signalling ions (see app note on Calcium Imaging), structure of cells and the electrical activity of neurons (see app note on Electrophysiology).

  • Rolling vs Global Shutter

    The shutter is a typical component of a camera, whether mechanical or electronic. For scientific cameras, mechanical shutters are typically slow and subject to maintenance as a frequently moving part, at Teledyne Photometrics our CCD, EMCCD, and CMOS scientific cameras use electronic shutters.

  • Introduction To Electrophysiology

    Electrophysiology is the study of electrical properties of biological cells and tissues, and can be broadly split into neural (nerves throughout the body, especially the spine and brain, also the retina) and cardiac (to do with the heart) electrophysiology. Electrophysiology is a vital tool in neuroscience, where the right tools can interrogate the activity of neurons and/or astrocytes as they communicate using electrical signals.

  • Super-Resolution Spinning Disk Confocal

    Dr. Joana Delgado Martins is a research associate at the Center for Microscopy and Image Analysis, a facility at the University of Zurich, which is run by Dr. Urs Ziegler. The center has recently acquired a new Olympus SpinSR SoRa system along with two Prime BSI cameras. Dr. Martins works closely alongside researchers to improve imaging in a variety of different applications.

  • Imaging Photon Bose-Einstein Condensate

    The Adaptive Quantum Optics Lab in University of Twente performs advanced research on the physics of quantum light for applications in (quantum) information science and technology. PhD student Chris Toebes works in this lab with photon Bose Einstein condensates (BECs).