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  • What Is Single Molecule Microscopy?

    While most fluorescent microscopy involves looking at hundreds or thousands of fluorophores spread throughout a sample, it is sometimes necessary to observe specific molecules or small groups of molecules.

  • What Is TIRF Microscopy?

    Total internal reflection (TIR) can occur when light is moving from one medium to a different medium e.g. air to glass, glass to water, water to oil. At certain angles, rather than being refracted into the new medium, the light is reflected back into the medium it came from.

  • Fluorescent Optical Projection Tomography

    Current methods used to construct 3D optical images are limited in the maximum thickness of certain samples. Confocal microscopy (in combination with two-photon approaches) is limited to ~1 mm depth, meaning that larger samples would have to be further sectioned and would not remain intact.

  • Fluorescence Recovery After Photobleaching (FRAP)

    Fluorescent markers become excited by specific wavelengths of light, and then emit light in a different wavelength. This makes them very valuable for scientific research in order to locate cells/proteins and even track them over time.

  • Förster Resonance Energy Transfer (FRET)

    Similarly to how two magnets will only attract each other when they are close enough, fluorescence energy can also be transferred between fluorescent molecules if they are in extremely close proximity. This is the principle behind Förster Resonance Energy Transfer (FRET), which is a technique used to determine whether two fluorescent molecules are within a certain distance of one another.

  • Light Sheet Microscopy at University of St. Andrews

    The Optical Manipulation Group at the University St. Andrews, led by Prof. Kishan Dholakia, looks at the science of light in terms of physics and biomedical research, fundamental and applied, in order to further the agenda for healthcare applications.

  • e2v’s new CMOS sensors feature the world’s smallest true global shutter

    e2v has launched its ground breaking new Emerald family of CMOS image sensors. This new product family features the world’s smallest true global shutter pixel available on the market today (2.8µm). With a smaller optical format and higher resolutions, the new sensors lead to improved performance and reduced system costs for customers.

  • Yokogawa Spinning Disk

    There are two significant challenges in biological imaging that conventional fluorescence microscopy cannot overcome. Firstly, biological specimens are 3D structures and in order to fully understand them, we often need to construct 3D images.

  • Quantum Communication

    The Integrated Quantum Photonics lab of Dr. Tim Schröder at the Humboldt-University of Berlin is interested in understanding, controlling, and developing use cases for quantum research. In this particular project, Maarten van der Hoeven is characterizing and studying the behavior of color centers in diamond nanostructures.

  • High-Speed Calcium Imaging

    The Volynski lab, led by Kirill Volynski, Professor of Neuroscience at University College London (UCL), is primarily interested in understanding the regulation of neurotransmitter release which forms the basis of communication among neurons in the brain.

  • Live Cell Dynamics

    The group of Prof. Cornelia Monzel aims to understand the interplay of physical and biological mechanisms that give rise to relevant cellular functions for use in diagnostics and therapy.

  • Neural Optogenetics

    Dr. Cruikshank and colleagues are interested in information processing in the brain, focusing on circuits linking the brain’s neocortex and thalamus. These circuits are critical to sensation, perception and learning.