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High-Throughput Spinning Disk Confocal
Dr. Tom Lummen is a microscopy engineer at ETH Zürich University, and spoke to us about the imaging facility he works with, “I’m part of the microscopy team that operates the imaging core facility, we provide 20 high-end automated microscopes for the imaging needs of the users of our department
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Neuronal Single-Molecule TIRF
Marco Schnieder is a PhD student in the group of Prof. Klingauf, whose research focuses on neuroscience, mainly the physiology of synaptic transmission, and the mechanisms of synaptic vesicle recycling, in particular endocytosis.
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Calcium and Voltage Imaging
Dr. Naoki Kogo is a visiting researcher in the lab of Prof. Nael Kasri, participating in projects to study the neural properties of network dysfunction in neurodevelopmental disorders.
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Dynamic Microfluidic Imaging
The Knowles Lab at the University of Cambridge is an interdisciplinary group that develops new approaches to probe the behavior of biological molecules, especially protein self-assembly, a process that can result in several neurodegenerative diseases when misfolding occurs.
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Light Sheet Optical Thermometry
Dr. Brian Patton and Ph.D. candidate Petros Hadjichristodoulou are involved in microscopy development and incorporating technologies into imaging. One such technology is the use of nanodiamonds (NDs), these contain natural defects known as nitrogen-vacancy centers that can be modulated by illuminating the NDs, which will emit fluorescence.
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High-Speed Single Molecule Light Sheet
The lab of Dr. Aleks Ponjavic develops fluorescence microscopy techniques in order to study live-cell samples, including particularly mechanically delicate and photosensitive samples such as T cells. These live samples undergo complex processes and require high-speed imaging, sensitivity, and nanoscale resolution in order to determine the behavior of individual proteins within the cells.
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Nematostella OPM Light Sheet
Dr. Rory Power is a staff scientist and engineer at the advanced imaging center of the EMBL headquarters in Heidelberg. Involved in a variety of projects, Dr. Power also oversees Ph.D. students involved in building custom light sheet imaging systems.
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Single Molecule Detection
The Shen lab at Kent State University are using single-molecule imaging approaches to evaluate catalytic reactivity of various carbon nanoparticle formulations. Electrochemical reactions are critical to energy conversion and storage, but mechanisms to understand key parameters at the molecular level have been lacking.
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Super-Resolution Single Molecule Localization
Single-molecule localization microscopy (SMLM) techniques, such as photoactivation localization microscopy (PALM), achieve some of the highest spatial resolutions among all the super-resolution imaging methods. However, image reconstruction in PALM requires a large number of raw images, which leads to low temporal resolution
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SRRF and Super-Resolution Microscopy
The Henriques group use various super resolution microscopy techniques to investigate cell signalling and host-pathogen interactions as well as creating and developing technology for cell biology research.A big challenge in super-resolution microscopy is the requirement for intense illumination but this is usually phototoxic and incompatible with live-cell imaging.
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STORM Super-Resolution
The laboratory of Dr. Rothenberg at the New York University School of Medicine focuses on new optical methods to study biological molecules and processes at real time and nanometer scale. The Rothenberg research team studies the mechanisms of enzymes and proteins that participate in repair of DNA damage leading to cancer, and develops new imaging methods that will enable them to visualize the behavior of individual biological molecules.
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Multifocus and Snouty Light Sheet Microscopy
Dr. Florian Ströhl leads a group of physicists to develop advanced microscopy systems, including a new light-sheet imaging system. This custom light-sheet system involves a single-objective oblique plane microscopy (OPM) approach using the Snouty lens, as well as additional capabilities for 3D imaging.