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Super-Resolution Single Molecule Localization
The Lew lab is creating technology to image multidimensional trajectories of individual molecules in time and space, with one focus on understanding the structural dynamics of amyloid aggregation in diseases like Alzheimer’s.In collaboration with Jan Bieschke, UCL, the lab has developed a single-molecule localization microscopy (SMLM) technique called TAB, transient amyloid binding, to image the structure of amyloid protein aggregates over periods of hours to days.
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diSPIM Light-Sheet
Prof. Matthias Weiss and PhD student Ivana Jeremic research challenging problems at the interface of physics and biology, focusing on understanding self-organization processes in living organisms.
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Dual-Color Voltage Imaging
Dr. Davide Raccuglia and his team use the model organism Drosophila melanogaster (colloquially known as fruit fly) to study how the brain regulates sleep. Dr. Raccuglia told us more about his research, “What I’m particularly interested in is the functional neural architecture of sensory gates for sleep regulation.
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Structured Illumination Microscopy (SIM)
Dr. Guy Hagen, Research Associate from the University of Colorado, Colorado Springs creates high performance image reconstruction methods and open-source software to process super-resolution microscopy data. In 2014 Dr. Hagen released ThunderSTORM, an ImageJ plug-in for automated processing of photo-activated localization microscopy (PALM) and stochastic optical reconstruction microscopy (STORM) data.1
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Super-Resolution Microscopy at University of California, Berkeley
The Ke Xu Group at the University of California Berkeley, College of Chemistry is an interdisciplinary lab that combines biophysics, physical chemistry and cell biology. Their goal is to understand how orders emerge in biological systems at the nano-meter scale from the interaction between biomolecules.
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3rd Party Software: Python
Python is a general-purpose, high-level, interpreted programming language that allows for quick and effective system integration through the use of dynamic typing and reference counting.
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3rd Party Software: EPICS for PICAM
EPICS is an Open Source project that is freely available and developed collaboratively from multiple scientific facilities. The powerful and reliable software makes it the preferred choice for applications using large scale, complex distributed control systems.
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3rd Party Software: Micro-Manager Open Source Microscopy Software
Micro-Manager is a software package for control of automated microscopes. Micro-Manager provides an inclusive, open source, imaging solution with image processing options available via the ImageJ application.
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3rd Party Software: Nikon NIS-Elements Software
Nikon offers a range of advanced microscope software solutions for performance optimization and control of each of its products, including NIS-Elements microscopy imaging software. Each software is easy-to-use and customizable without compromising on performance to meet specific application requirements.
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PVCAM Online Documentation
The PVCAM API documentation is part of the PVCAM SDK installer and is also available online.
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Download Beacon 2.1.228.0 (Windows)
Beacon is free of charge and enables users to configure and control scientific camera, verify functionality, and execute basic imaging experiments.
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Download Beacon 2.1.228.0 (Linux)
Beacon is free of charge and enables users to configure and control scientific camera, verify functionality, and execute basic imaging experiments.