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  • Starlight Image Sensor Technology

    Low-light applications require sufficient video throughput, signal-to-noise ratio, and spatial resolution to allow human interpretation of a complex scene passing through the digitization channel. It is therefore essential that the pixels be of optimum size and highly sensitive: every photon counts.

  • High-Speed Retinal Voltage Imaging - meta

    Dr. Guilherme Testa-Silva is head of Physiological Technologies at 1OB, part of a group committed to developing groundbreaking therapies for restoring sight. meta

  • High Harmonic Generation Metasurface Imaging

    Falco Bijloo is a PhD student in the nanophotonics group of Dr. Femius Koenderink at AMOLF, researching how to generate harmonics and make non-linear metasurfaces.

  • Monkey Brain Calcium Imaging

    The lab of Prof. Cody Siciliano works to develop animal models and determine the neural basis of motivation, addiction, and decision making.

  • SCAPE Microscopy

    In 2015 Prof. Elizabeth Hillman and team developed swept confocally-aligned planar excitation microscopy, or SCAPE (Bouchard et al. 2015). SCAPE is a single-objective light-sheet imaging method designed for high-speed volumetric 3D imaging, without moving the objective or sample. A sweeping light sheet synchronized with fast camera acquisition offered true volumetric imaging at unprecedented speeds.

  • 3D Live Cell SCAPE

    The lab of Prof. Alf Honigmann focuses on the organisation and function of cell interfaces across scales. We spoke with postdoctoral researcher Dr. Markus Mukenhirn and Master’s student Pierre DeMarinis about their work in the Honigmann lab. Dr. Mukenhirn explained, “I work with mouse embryonic stem cells (mESCs) to study how they self-organise into 3D structures and the dynamics of their growth, observing them under the microscope over several days. By employing single-objective light sheet microscopy, we capture high resolution live-cell dynamics, revealing the intricate processes of lumen formation and tissue organization.”

  • Fluorescence Diffraction Tomography

    Prof. Yi Xue and team at UC Davis develop custom optical microscopy techniques for brain imaging and optogenetic stimulation, tailored to maximize throughput, spatial resolution, imaging depth, and imaging speed.

  • Astronomy with Adaptive Optics

    Dr. Jared Males is an astronomer who works at the Steward Observatory, studying extrasolar planets, “Extrasolar planets are planets orbiting stars other than our sun, I image them using adaptive optics and coronagraphs. We want to take direct pictures of those planets, split the light from the planet, separate it from the star, and measure the properties of the planet's atmosphere, specifically looking for things like: does it have oxygen, does it have water, does it have methane, how hot is the planet.”

  • 3D Light Sheet Organoid Imaging

    Prof. Miao Ping Chien’s laboratory at the Erasmus University Medical Center Rotterdam is exploring the molecular mechanisms behind rare and aggressive cancer cell subpopulations, as well as cancer cell states that contribute to the tumor progression, metastasis and therapy resistance. The multidisciplinary approach uses a combination of microscopy, AI assisted image analysis, bioinformatics as well as single cell and spatial-omics technologies. This aims to translate findings on the cellular level to clinical applications.

  • Imaging Flat Jet Liquid-Liquid Interfaces

    Professor Andreas Osterwalder is a group leader whose research is mainly focused on novel methods of producing cold neutral molecules and leveraging their usage in fundamental chemical and physical research, as well as targeting interfaces between two liquids, and dynamical processes taking place in such environments.

  • Whole Brain Super-Resolution 3D FISH

    Dr. Marcelo Nollmann leads a research group at the Centre national de la recherche scientifique (CNRS) in Montpellier, where his group aims to develop single-molecule and advanced microscopy methodologies to understand the mechanisms underlying DNA organisation and transcription in multi-cellular organisms.

  • Micro-Manager Guide

    A guide to imaging software Micro-Manager