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Novel Structured Illumination Microscopy
Prof. Bernd Rieger works with applied physics at TU Delft, and tells us about his research, “We are an applied physics and engineering group researching computational microscopy and building microscope systems, improving spatial resolution and temporal resolution of imaging systems. We start with empty optical tables and then build our systems.”
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Fluorescence and Electrophysiology
Prof. Naoki Yamawaki is a neuroscientist at Aarhus University, who told us about his research, “We are interested in understanding how stress affects the neuronal connections and communication in the brain, I am responsible for running the lab, doing experiments, mentoring, teaching students, and more.
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NIR/VIS Brain Imaging
The lab of Professor Marc Spehr is working on the olfactory system of mammals and the underlying mechanisms of pheromone detection. Pheromone detection is key for social communication in the animal world
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Advice On Choosing A Camera For Calcium Imaging
The key specifications to look for in a camera for calcium imaging will depend broadly on the type of calcium imaging being performed. From the perspective of the camera, the simplest way to divide calcium imaging would be into two application areas; neuronal calcium imaging and cardiac calcium imaging.
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Digital Interfaces
Digital interfaces allow scientific cameras (and other imaging or microscopy hardware) to communicate with computers, typically for data transfer so that images acquired during experimentation can be stored for analysis and processing.
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Intrinsic Signal Optical Imaging
The brain is one of the most complex objects in the known universe, both in terms of structure and function. This makes imaging the brain an incredibly challenging task, with researchers looking at the movement of signalling ions (see app note on Calcium Imaging), structure of cells and the electrical activity of neurons (see app note on Electrophysiology).
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Rolling vs Global Shutter
The shutter is a typical component of a camera, whether mechanical or electronic. For scientific cameras, mechanical shutters are typically slow and subject to maintenance as a frequently moving part, at Teledyne Photometrics our CCD, EMCCD, and CMOS scientific cameras use electronic shutters.
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Introduction To Electrophysiology
Electrophysiology is the study of electrical properties of biological cells and tissues, and can be broadly split into neural (nerves throughout the body, especially the spine and brain, also the retina) and cardiac (to do with the heart) electrophysiology. Electrophysiology is a vital tool in neuroscience, where the right tools can interrogate the activity of neurons and/or astrocytes as they communicate using electrical signals.
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Super-Resolution Spinning Disk Confocal
Dr. Joana Delgado Martins is a research associate at the Center for Microscopy and Image Analysis, a facility at the University of Zurich, which is run by Dr. Urs Ziegler. The center has recently acquired a new Olympus SpinSR SoRa system along with two Prime BSI cameras. Dr. Martins works closely alongside researchers to improve imaging in a variety of different applications.
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Imaging Photon Bose-Einstein Condensate
The Adaptive Quantum Optics Lab in University of Twente performs advanced research on the physics of quantum light for applications in (quantum) information science and technology. PhD student Chris Toebes works in this lab with photon Bose Einstein condensates (BECs).
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X-ray Beam Characterisation
Dr. Roelof van Silfout is a researcher at KU Leuven, working on a variety of projects mostly concerning x-rays. Dr van Silfout explained one of his experiments, “We are interested in defining or measuring the position of a hard x-ray beam.
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Optogenetics
Neurons in the brain communicate with chemical and electricity signals. Neuroscience has developed numerous probes and electrodes in order to detect this activity, and try to figure out what the neurons in each brain area do.